Management Team

Ming Wang, PhD/MBA
Ming Wang, PhD/MBA
Founder and CEO

Dr. Ming Wang is Founder, President and CEO of Phanes Therapeutics, Inc. based in San Diego. The company focuses on drug discovery and development to treat cancer and metabolic complications. Ming was formerly Vice President and Disease Area Leader of Diabetes/Metabolism in Janssen, the pharmaceutical sector of Johnson & Johnson, with global responsibility for the diabetes portfolio (from discovery stage to phase 2). In this role, he was responsible for setting strategies for internal innovation and external partnerships, making investment decisions and building a portfolio of assets for disease treatment and prevention. Under his leadership, J&J built a strong pipeline of metabolic assets ranging from discovery stage programs to clinical assets. During his tenure at J&J, Ming’s team built many external partnerships with biotech companies and academic institutions, including a licensing agreement with Hanmi Pharmaceuticals on a phase 1 clinical candidate with an upfront payment of $105 million in 2015. Ming was also the champion in formulating a strategy for NASH (non-alcoholic steatohepatitis) and other metabolic disease areas for the group. Previously, Ming was Executive Director and Head of Diabetes Research at Amgen where he headed a group of ~50 scientists located in Amgen’s headquarter (Thousand Oaks) and San Francisco, working on developing novel therapies for metabolic diseases. Before joining Amgen, Ming championed drug discovery programs in cardiovascular and metabolic diseases and managed corporate partnerships in Parke-Davis, Pfizer and Pharmacia.

Ming served on multiple advisory boards, including the Scientific Advisory Board (SAB) of Amgen Ventures ($100 million in management). He is a frequent organizer and speaker of biotech and pharma conferences and has 59 publications and a book entitled “Metabolic Syndrome: underlying mechanisms and drug therapies” (publisher: John Wiley & Sons, Inc.). He is an Associate Editor of Frontiers in Experimental Pharmacology and Drug Discovery. Ming is also an adjunct faculty in the Department of Bioengineering and Therapeutic Sciences at the University of California, San Francisco Schools of Pharmacy and Medicine. He holds a PhD in Biochemistry and a MBA in General Management.

Hui Zou, PhD
Hui Zou, PhD
Chief Scientific Officer (CSO)

Dr. Hui Zou is an experienced and accomplished oncologist in both academia of biological research and industry of drug development. Before joining the industry, Hui was a tenured Associate Professor of the Department of Molecular Biology at UT Southwestern Medical Center. He was awarded American Cancer Society Research Scholar and Kenneth G. and Elaine A. Langone Scholar of Damon Runyon Cancer Research Foundation. His work was supported by NIH R01 and other private and public foundations. Before joining UT Southwestern Medical Center, Hui was a postdoctoral fellow in the laboratory of Marc W. Kirschner at Harvard Medical School. He was a fellow of Jane Coffin Childs Memorial Fund for Medical Research. As a graduate student, postdoctoral fellow and independent PI, Hui made important discoveries in the mechanism of sister chromatid recombination, cohesion and separation during mitosis. His discoveries generated many important publications, including 4 manuscripts published in Science or Cell as first or corresponding author.
Hui joined the industry in 2012 to translate his scientific expertise into biomedical drug discovery and development. Hui joined Phanes in 2017 and currently is the Chief Scientific Officer (CSO) and Executive VP. As the Head of R&D, Hui oversees the drug discovery and the process development teams. As his first position in the industry, Hui became Senior Director at Crown Biosciences in 2012. He led a team of 20 biologists and chemists in two integrated service projects contracted by Eli Lilly. Both projects leveraged novel cell cycle regulators to treat cancers, one of which has been advanced by Lilly into clinical development.
Hui holds a PhD degree of genetics and development from Columbia University.